NMR Spectroscopy

Probengeber NMR

NMR spectroscopy is one of the leading methods for structure elucidation of organic compounds. Regardless of whether the focus is on synthesis control, analyzing competitor samples, identifying unknown secondary components or determining the content of pure substances and mixtures, we provide support for the entire cycle – from research and development right through to production and quality assurance.


5 NMR devices

  • 2 x 400 MHz Avance III
  • 1 x 600 MHz Avance Neo
  • 1 x 600 MHz Avance III HD
  • 1 x 700 MHz Avance III

Routine NMR spectroscopy

  • In the case of long-term experiments, nitrogen reliquefaction ensures special stability

High-field NMR spectroscopy

  • 600 MHz and 700 Mhz high-field spectrometer devices equipped with state-of-the-art cryotechnology

Routine NMR spectroscopy

  • Cost-effective high throughput thanks to consistent automation – even at 700 MHz
  • Gradient technology for fast, artifact-free 2D NMR spectra
  • High-temperature broadband cryogenic probe head for maximum sensitivity in the case of X-NMR spectra
    (z. B. 13C, 29Si, 31P, 19F)
  • All standard 1D and 2D NMR experiments are available at a fixed price

High-field NMR spectroscopy

  • 700 MHz spectrometer with state-of-the-art cryogenic probe head
  • Optimum spectral resolution and sensitivity – leading European NMR service laboratory

Quantitative NMR spectroscopy

  • Maximum precision and reliable results based on many years of experience
  • Fast and cost-effective alternative to chromatographic methods
Areas of application

Pharmaceuticals / crop protection

  • Fast and cost-effective qualification of reference substances
  • Identity and content from one analysis

  • Analyses can be performed under GMP and GLP

Polymer analytics

  • Structural elucidation also of complex (co)polymer systems (monomers, terminal groups, crosslinkers, chain length, tacticity)
  • Identification of low-molecular components (e.g. reactive diluents, UV initiators, etc.) with DOSY-NMR (diffusion-ordered spectroscopy)

Trace analytics

  • Highly selective quantitative determination of impurities down to the ppb range
  • Structural elucidation of the smallest substance quantities (e.g. metabolites from prep. HPLC)

Catalyst research

  • Direct information on the condition of catalyst systems from heteronuclear NMR spectra
  • Thanks to ATM technology, even “unusual” nuclei (e.g. 119Sn, 195Pt, 207Pb, etc.) can be measured “at the touch of a button”

Online reaction monitoring

  • Time resolution of less than 1 min under realistic conditions (pressure, temperature) is possible
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